Inhibitors for Metastasis and Angiogenesis

Adhesion

Cat.No	Product	Action
2524	A 205804	Selective inhibitor of E-selectin and ICAM-1 expression
1903	Peptide F9	Inhibits laminin-mediated cell adhesion and migration
1567	Thiolutin	Antibiotic. Inhibits vitronectin cell adhesion

Migration

Cat.No	Product	Action
2621	ARP 100	Selective inhibitor of MMP-2
2622	ARP 101	Selective inhibitor of MMP-2
1760	(±)-Blebbistatin	Selective inhibitor of myosin II
1853	(R)-(+)-Blebbistatin	Inactive enantiomer of the myosin II inhibitor (±)-blebbistatin (Cat. No. 1760)
1852	(S)-(-)-Blebbistatin	Selective inhibitor of myosin II. Active enantiomer
0541	Fasudil hydrochloride	Inhibitor of cyclic nucleotide dependent- and Rho-kinases
2570	Kisspeptin 10	Endogenous ligand for KISS1 receptor (hOT7T175/AXOR12/GPR54)
2414	H 1152 dihydrochloride	Selective rho-kinase (ROCK) inhibitor
2485	Glycyl-H 1152 dihydrochloride	More selective analogue of Cat. No. 2414
2415	HA 1100 hydrochloride	Cell-permeable, selective Rho-kinase inhibitor
2631	Marimastat	Broad spectrum MMP inhibitor
1443	Metastin (human)	Potent, endogenous ligand for KISS1 receptor (hOT7T175, AXOR12 and GPR54)
0431	ML 9 hydrochloride	Myosin light chain kinase inhibitor
1926	MLCK inhibitor peptide	Myosin light chain kinase inhibitor
1885	MLCK inhibitor peptide 18	Selective inhibitor of myosin light chain kinase
2161	NSC 23766	Selective inhibitor of Rac1-GEF interaction; antioncogenic
2067	187-1, N-WASP inhibitor	Inhibits actin assembly
2520	PD 166793	Broad spectrum matrix metalloproteinase (MMP) inhibitor
2222	Rac1 Inhibitor F56, control peptide	Control peptide version of Rac1 Inhibitor W56 (Cat. No. 2221)
2221	Rac1 Inhibitor W56	Selective inhibitor of Rac1-GEF interaction
0369	W-7 hydrochloride	Calmodulin antagonist. Inhibits myosin light chain kinase
2633	WAY 170523	Potent and selective inhibitor of MMP-13
1254	Y-27632 dihydrochloride	Selective p160ROCK inhibitor

Angiogenesis

Cat.No	Product	Action
1768	Fumagillin	Methionine aminopeptidase-2 inhibitor
2392	JTE 013	S1P2 receptor antagonist
2542	Ki 8751	Potent, selective VEGFR-2 inhibitor
1807	2-Methoxyestradiol	Apoptotic and antiangiogenic agent
0665	L-NAME hydrochloride	Non-selective NOS inhibitor
0546	L-NIO dihydrochloride	Potent eNOS inhibitor
0880	ODQ	Selective inhibitor of NO-sensitive guanylyl cyclase
2284	SEW 2871	Cell-permeable, selective S1P1 receptor agonist
1472	Suramin hexasodium salt	Non-selective P2 antagonist
1415	1400W dihydrochloride	Potent, highly selective iNOS inhibitor
2499	ZM 306416 hydrochloride	Inhibitor of VEGF receptor tyrosine kinase
2475	ZM 323881 hydrochloride	Potent, selective inhibitor of VEGFR-2

• Anti-cancer Agents