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 Á¦Ç°¾È³»  ¸é¿ªÇР  Cell Biology  Actin/Tubulin Research

FtsZ protein

FtsZ (Filamenting temperaturesensitive mutant Z)´Â ÁøÇÙ¼¼Æ÷ÀÇ Æ©ºÒ¸°¿¡ ¹ÝÀÀÇϸç, ÃÖÃÊ·Î ¹ß°ßµÈ ¿øÇÙ¼¼Æ÷ÀÇ ¼¼Æ÷°ñ°Ý ´Ü¹éÁú·Î ¼¼Æ÷ºÐ¿­½Ã ¼¼Æ÷ »çÀÌ¿¡ ±¸¼ºµÇ´Â »õ·Î¿î ¼¼Æ÷º®À» ¸¸µé±â À§ÇØ ´Ù¸¥ Á¾·ùÀÇ ´Ü¹éÁúÀ» ºÒ·¯µéÀ̴µ¥ ÇʼöÀûÀÔ´Ï´Ù.

Cytoskeleton»çÀÇ FtsZ proteinÀº FtsZ binding proteinsÀ» µ¿Á¤Çϴµ¥ »ç¿ëµÇ¸ç, ´Ù¾çÇÑ species·ÎºÎÅÍ ºÐ¸®µÈ ´Ü¹éÁúÀ» Á¦°øÇÕ´Ï´Ù.

Cytoskeleton
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    FtsZ species % Homology to E. coli Cat. No.
    Escherichia coli 100 FTZ01, FTZ05
    Salmonella enterica 99 NA
    Staphylococcus aureus 47 FTZ02
    Streptococcus pneumoniae 50 FTZ03
    Enterococcus faecalis 49 FTZ04
    Àû¿ë
    Figure 1 - Polymerization of 0.5 mg/ml FtsZ protein from E.coli (panel A) and S.aureus (panel B) in the presence of 15 mM FtsZ inhibitor PC190723 (red line) or HEPES250 buffer (green line). GTPase activity was measured with a MESG-based assay (Cat. # BK052). See references (25-27) for additional details.