• Home
  • About us
  • Log-In
  • Join Us
  • Sitemap
  • Recruit
제품/실험 Q&A
자주묻는질문
자유게시판
실험기법
자료신청
논문자료
클레임 접수
기기 A/S 접수
클레임 진행조회
 제품안내  항체,항원,킷트   Cancer Research  Epigenetics

Recombinant Nucleosomes

뉴클레오좀(Nucleosome)은 Chromatin과 상호작용하거나 이를 변형시키는 reader, writer, eraser의 생리학적 타겟입니다. Epicypher는 Epigenetics study를 위한 다양한 DNA 및 Histone modification으로 구성된 recombinant human nucleosome을 제공합니다.

EpiCypher
제품 문의하기
인쇄하기



  Designer Nucleosome (dNucs™)
  • Histone의 특정한 위치에 이미 acetylation, methylation등의 PTM이 진행된 recombinant nucleosome 입니다.
  • 타겟 enzyme/protein에 대한 substrate로 이용될 수 있습니다.
  • lot-to-lot variation 이 낮아 높은 재현성을 보여줍니다.
  • Free DNA가 포함되지 않아 안정성이 높습니다.
  • Biotinylated, Non-biotinylated dNucs이 있습니다. 
  Recombinant Nucleosome (rNucs™)
  • PTM이 진행되지 않은 Fully recombinant nucleosome 입니다.
  • Inhibitor testing, enzyme assay등에 이용됩니다.
  Oncogenic Nucleosomes (oncoNucs™)
  • 특정 histone에 amino acid를 다른 시퀀스로 치환하여 제공되는 recombinant nucleosome 입니다.
  • enzyme activity에 있어 mutation의 효과를 스터디하는데 유용합니다.
  Histone Variant Nucleosomes (vNucs™)
  • Histone varients를 포함하고 있는 recombinant nucleosome 입니다.
  Chromatin Remodeling Assay Substrate (EpiDyne™)
  • In vitro Nucleosome Remodeling (repositioning)을 모니터링 하는데 이용되는 nucleosome 입니다.
  • Histone을 감싸고 있는 DNA의 5'말단을 Cy3로 처리하고, Histone octamer는 Cy5로 라벨링되었습니다.
  • Histone octamer가 재배치 되거나 방출될때 Cy5가 소실되므로 Cy3-Cy5 FRET의 원리를 통해 확인합니다.













주문정보(Ordering Information)
CATNUM PRODUCT SIZE
16-0004Chicken Oligonucleosomes, Purified50ug
16-0002HeLa Mononucleosomes, Purified50ug
16-0003HeLa Polynucleosomes, Purified50ug
16-0001Histone Octamer, Recombinant Human50ug
16-0017Mononucleosomes (H3.3 Î N32), Human Recombinant Biotinylated50 ug
16-0011Mononucleosomes (H3.3), Human Recombinant Biotinylated50 ug
16-0018Mononucleosomes (H4 Î N15), Human Recombinant Biotinylated50 ug
16-0009Mononucleosomes, Recombinant Human100 ug
16-0006Mononucleosomes, Recombinant Human Biotinylated50ug
16-0362Nucleosome, Recombinant Human, H3 Cit2,8,17 dNuc, Biotinylated50ug
16-0317Nucleosome, Recombinant Human, H3 K27me3 dNuc50ug
16-0322Nucleosome, Recombinant Human, H3 K36me1 dNuc50ug
16-1319Nucleosome, Recombinant Human, H3 K36me2 dNuc, Non-biotinylated50ug
16-0320Nucleosome, Recombinant Human, H3 K36me3 dNuc50ug
16-0321Nucleosome, Recombinant Human, H3 K4me1 dNuc50ug
16-0334Nucleosome, Recombinant Human, H3 K4me2 dNuc50ug
16-0325Nucleosome, Recombinant Human, H3 K9me1 dNuc50ug
16-0315Nucleosome, Recombinant Human, H3 K9me3 dNuc50ug
16-0341Nucleosome, Recombinant Human, H3 R2me2a dNuc50ug
16-0345Nucleosome, Recombinant Human, H3 S10phos dNuc50ug
16-0372Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated50ug
16-0373Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated50ug
16-0364Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated50ug
16-0338Nucleosome, Recombinant Human, H3K27me1 dNuc50ug
16-0339Nucleosome, Recombinant Human, H3K27me2 dNuc50ug
16-1317Nucleosome, Recombinant Human, H3K27me3 dNuc, Non-biotinylated50ug
16-0319Nucleosome, Recombinant Human, H3K36me2 dNuc50ug
16-1320Nucleosome, Recombinant Human, H3K36me3 dNuc, Non-biotinylated50ug
16-0336Nucleosome, Recombinant Human, H3K4,9,14,18ac dNuc Biotinylated50ug
16-1334Nucleosome, Recombinant Human, H3K4me2 dNuc50ug
16-0316Nucleosome, Recombinant Human, H3K4me3 dNuc50ug
16-0335Nucleosome, Recombinant Human, H3K4me3, K9,14,18ac dNuc, Biotinylated50ug
16-0367Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated50ug
16-0369Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated50ug
16-1314Nucleosome, Recombinant Human, H3K9ac dNuc50ug
16-0314Nucleosome, Recombinant Human, H3K9ac dNuc50ug
16-0371Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated50ug
16-0324Nucleosome, Recombinant Human, H3K9me2 dNuc50ug
16-0340Nucleosome, Recombinant Human, H3R2me1 dNuc50ug
16-1345Nucleosome, Recombinant Human, H3S10ph dNuc, Non-biotinylated50ug
16-0312Nucleosome, Recombinant Human, H4 K12ac dNuc 50ug
16-0331Nucleosome, Recombinant Human, H4 K20me1 dNuc50ug
16-0332Nucleosome, Recombinant Human, H4 K20me2 dNuc50ug
16-0333Nucleosome, Recombinant Human, H4 K20me3 dNuc50ug
16-0313Nucleosome, Recombinant Human, H4 Tetraacetyl (H4K5, 8, 12, 16 Ac) dNuc50ug
16-0353Nucleosome, Recombinant Human, H4K8ac dNuc, Biotinylated50ug