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 제품안내  면역학   Stem Cell

hiPSC-derived neural cells

hiPSC-derived Dopaminergic/Motor neuron과 Astrocytes를 공급합니다

Axol
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   1. Human iPSC-Derived Dopaminergic Neuron Progenitor Kit

특징

  • 해동 후 12일 후에 mature dopaminergic neurons 생성
  • Cell population 구성: 65-80% TUJ1+ neurons, 15-30% tyrosine hydroxylase (TH)+ dopaminergic neurons, <5% GFAP+ astrocytes
  • Maintenance Medium에 40일 동안 유지할 수 있음
  • Electrically active dopaminergic neurons를 얻기 위해서는 5주 culture
  • Specification

          Donor age: Newborn Male
          Starting material: Cord blood CD34+ cells
          Size: >1M cells

 
 

  2. Human iPSC-derived Motor Neuron Progenitors

특징

  • Progenitor cell은 Motor neuron cell fate markers (OLIG2과 SOX1) 발현
  • Mature stage에서는 Motor neuron의 대표적인 마커인 HB9, LIM3 그리고 ChAT를 발현함
  • 배양에 필요한 media 제공
  • Specification

          Donor age: 74 yrs Male
          Starting material: Fibroblasts
          Size: ≥2 million cells


적용
  • Mature motor neuron의 마커 HB9, LIM3 and ChAT의 발현 (Immunocytochemistry)



     

 

   3. Human iPSC-derived Astrocytes

특징

  • 세포의 80%가 GFAP+ (Glial Fibrillary Acidic Protein), 나머지 ≤15%는 TUJ1+ (neuronal class III ß-tubulin) neurons로 구성
  • hiPSC-derived Astrocytes 전용 maintenance medium: ax0086  Astrocyte Maintenance Medium (100 mL) (including Supplement A, Supplement B and Supplement C)
  • Specification

          Donor age: Newborn
          Starting material: CD34+ cord blood
          Size: ≥1 million cells


적용
  • Immunocytochemistry를 이용한 마커 발현의 비교


      

주문정보(Ordering Information)
CATNUM PRODUCT SIZE
ax0086Astrocyte Maintenance Mediumea
ax4001Dopaminergic Neuron Induction Mediaea
ax0092Dopaminergic Neuron Maintenance Mediumea
ax0083Human iPSC-Derived Astrocyte Progenitor Kitea
ax0091Human iPSC-Derived Dopaminergic Neuron Progenitor Kitea
ax0084Human iPSC-Derived Mature Astrocyte Kit ea
ax0078Human iPSC-Derived Motor Neuron Progenitorsea
ax0072Motor Neuron Maintenance Mediumea
ax0071Motor Neuron Recovery Mediumea